| - | A Means to the Ends: Telomerase RNA Restores Telomere Length in Dyskeratosis Congenita
Telomerase RNA levels are involved in telomere shortening in X-linked dyskeratosis congenita |
| - | Antipsychotic Medications Same As Placebo For Alzheimer’s Patients
First phase of a large-scale clinical trial demonstrates that while some Alzheimer's Patients can benefit from antipsychotic medications, most do not. |
| - | Misfolded Protein Clumps Common in Lou Gehrig’s Disease
Researchers discover misfolded protein TDP-43 as a constituent part of the clumps that form in dementia providing new insights into the pathogenesis of neurological disorders. |
| - | A Gene Mutation May Control Sensitivity to Alcohol
Fruit fly study identifies mutation in white rabbit gene that regulates sensitivity to alcohol. |
| - | Ragweed Allergy Sufferers Can Benefit From Experimental Therapy
An experimental ragweed allergen immunotherapy shortens the time required to treat symptoms. |
| - | A Link Between Cyclic Nucleotide Metabolism And Depression
Genetic variants of phosphodiesterase 11 are associated with the diagnosis of depression and with patient responsiveness to antidepressant therapy. |
| 2006-10-13 |
| - | Detecting Disease-Causing Mutations in the Human Genome by Haplotype Matching
The authors describe a new strategy for detecting mutations that is based on comparing affected haplotypes with closely matched control sequences from healthy individuals, rather than with the human reference genome. |
| - | PLA2G6 Mutation Underlies Infantile Neuroaxonal Dystrophy
The study findings highlight a role of phospholipase in neurodegenerative disorders. |
| - | A Novel Mutation in FGFR3 Causes Camptodactyly, Tall Stature, and Hearing Loss (CATSHL) Syndrome
Abnormal FGFR3 signaling can cause human anomalies by promoting as well as inhibiting endochondral bone growth. |
| - | Systems Biology Tackles The Mechanisms Of Cancer
Potential novel targets for anti-cancer therapy are revealed. |
| - | Itching And Scratching
Dust mites produce an allergen that disrupts the skin's ability to act as a barrier to other allergens and environmental irritants. |
| - | Recommendations Help Identify Patients Suitable For NSAID Treatment
Recommendations should help physicians to identify quickly whether or not a patient is suitable for treatment with nonsteroidal anti-inflammatory drugs (NSAIDs). |
| - | Focus On Childhood Developmental Disorders
A special focus issue on childhood developmental disorders, including specific language impairment and dyslexia, autism, and the mental retardation syndrome fragile X, is presented. |
| - | New Strategy For Controlling Inflammation
A previously unknown method of terminating immune responses is reported. |
| - | New Breast Cancer Susceptibility Gene Identified
Women with mutations in a gene called BRIP1 have twice the normal risk of breast cancer. |
| - | One Step Toward More Efficient Cloning
A one-step somatic cell nuclear transfer procedure using a differentiated cell as a nuclear donor is reported for the first time. |
| - | Controlling The Insulin-Degrading Enzyme May Relieve Alzheimer's Disease
The structure of an enzyme that degrades insulin and amyloid-beta suggests a possible way to design drugs that combat the abnormal levels of these proteins in sufferers of diabetes or Alzheimer's disease. |
| - | Drug Target For Obesity?
A molecule that makes mammals feel full up has been identified. |
| 2006-10-02 |
| - | Potential Cure for Type 1 Diabetes in Islet Transplantation
Clinical Trial Shows Islet Transplantation is a Promising Procedure For Certain Patients with Severe Type 1 Diabetes |
| - | H9N2 Avian Flu Vaccine Paired with Adjuvant Provokes Strong Human Immune Response
Clinical trial reports that when combined with an adjuvant, low doses of an experimental vaccine against a strain of avian influenza (H9N2) provoked a strong antibody response in human volunteers. |
| - | Another Gene Implicated in Cleft Lip and Palate
Underexpression of SUMO1 can cause the world's most common birth defect, cleft lip and palate. |
| - | Connectivity Map
Using gene-expression signatures to connect small molecules, genes, and disease |
